B.Sc. Zoology
7th Semester Syllabus
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MJC-13 (T) : Molecular Biology
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Unit 1: Basics of Nucleic Acid
◦Central Dogma of Molecular Biology
◦Structure of DNA
◦DNA forms
◦Repetitive DNA
◦Structure and functions of mRNA, tRNA, and rRNA
Unit 2: DNA replication and repair
◦DNA replication in prokaryotes
◦DNA repair
◦Mismatch repair
◦Base excision repair (BER)
◦Nucleotide excision repair (NER)
◦Difference between prokaryotic and eukaryotic replication (A brief account)
Unit 3: Transcription
◦Mechanism of transcription in prokaryotes
◦Difference between prokaryotic and eukaryotic transcription (A brief account)
Unit 4: Translation
◦Genetic code
◦Degeneracy of genetic code and Wobble hypothesis
◦Structure of ribosomes
◦Mechanism of translation in prokaryotes
◦Difference between prokaryotes and eukaryotes translation (A brief account)
Reference Books:
- Becker, W.M., Kleinsmith, L.J., Hardin. J. and Bertoni, G. P. (2009). The World of the Cell. VII Edition. Pearson Benjamin Cummings Publishing, San Francisco
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter: Molecular Biology of the Cell, IV Edition
- Cooper G. M. and Robert E. Hausman R. E. The Cell: A Molecular Approach, V Edition, ASM Press and Sinauer Associates
- De Robertis, E.D.P. and De Robertis, E.M.F. (2006). Cell and Molecular Biology. VIII Edition. Lippincott Williams and Wilkins, Philadelphia
- Karp, G. (2010) Cell and Molecular Biology: Concepts and Experiments. VI Edition. John Wiley and Sons. Inc