Chemistry3rd Sem

B.Sc. Chemistry

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B.Sc. Chemistry

3rd Semester Syllabus

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MJC-3 (T) : Organic Chemistry: Cyclic Hydrocarbons and their Halogen Derivatives

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Unit 1: Reaction intermediates
Carbenes
Nitrenes and benzynes: Generation
Structure
Stability and reactions
Unit 2: Chemistry of Cyclic Hydrocarbons
Nomenclature of monocyclic and bicyclic compounds
Baeyer's strain theory
Conformation of cyclohexane
Relative stability of chair
Boat and twist boat forms of cyclohexane with their energy level diagram
Relative stability of mono- and disubstituted cyclohexanes
Aromaticity and Huckel rules with reference to benzenoids
Cyclocarbocations and cyclocarbanions
Mechanism of electrophilic aromatic substitution in benzene-halogenation
Nitration
Sulphonation
Friedel-Crafts alkylation/acylation
Energy profile diagrams of these reactions
Reactivity of mono-subsituted benzene
Directive influence of functional groups
Unit 3: Chemistry of Halogen Derivatives of alkanes
General methods of preparation
Properties and uses of mono- and dihalo derivatives of alkanes
Mechanism of substitution and elimination reactions viz
SN1, SN2, SN1, E1, E2 and E1CB mechanism
Unit 4: Halogen derivatives of arenes
General methods of preparation
Properties and uses of halogen derivatives of arenes
Mechanism: ArSN2
ArSN1
Elimination-addition mechanism (benzene mechanism)
Reference Books:
  • Reaction Mechanism in Organic Chemistry - S. M. Mukherjee and S.P. Singh
  • Organic Chemistry, vol.-1, I. L. Finar
  • Organic Chemistry - Morrison & Boyd
  • Organic Chemistry: Graham Solomons
  • Organic Chemistry: Paula Yurkamis Bruice
  • Stereochemistry in Organic Chemistry: D. Nassipuri
  • Stereochemistry- Conformation and Mechanism: P.S.Kalsi
  • Advanced Organic Chemistry, Fourth Edition, J. March, Wiley, India (2006)
  • Greeves, N., Clayden, J.; Warren, S., Organic Chemistry, 2nd Ed., Oxford University, Press India (2014)
  • Sykes, P., A Guidebook to Mechanism in Organic Chemistry, 6th Ed., Pearson Education India (2003)